Among the most common cancer types around the world, prostate cancer has strong genetic associations. Thereby, is the reason to develop therapeutics for the condition, as metastatic castrate-resistant prostate cancer came up.
What is Rucaparib?
Rucaparib tablets are given to adults on their doctor’s prescription for:
- The treatment and its maintenance of ovarian and fallopian tube cancer
- Primary peritoneal cancer when cancer comes back and the patients who are in response (complete or partial response) to platinum-based chemotherapy.
Is Rucaparib approved by FDA?
Yes, FDA (the U.S. Food and Drug Administration) has approved Rucaparib. It was done to make the monotherapy treatment of patients who are suffering from deleterious BRCA mutation-associated advanced ovarian cancer. And those who have been administered with chemotherapies that are two or more in number.
Is Rucaparib generic available in India?
Yes, Rucaparib generic version is available in India as a tablet and has proved to be the very first cost effective treatment for the disease. The cost of therapy is less expensive than the drugs already existing in the medicine market. BDR Pharma claim to launch India’s first generic Rucaparib with the brand name of BDPARIB.
How Rucaparib works
Rucaparib is a PARP inhibitor. PARP stands for polyadenosine diphosphate-ribose polymerase. It is an enzyme found in our cells that helps repair damaged DNA cells.
Rucaparib works by stopping the PARP protein from doing its repair work in cancer cells and the cell dies.
Rucaparib Brands in India
Here are the two pharmaceutical brands of India that bring this medicine in the market –
BDPARIB: Manufacturer by BDR Pharma
BDR Pharmaceutical launched BDPARIB to treat advanced ovarian and prostate cancers. And today, BDPARIB is the first affordable generic in India available in the form of a tablet, with the cost of therapy less expensive than any existing drugs in the market.
BDPARIB is a breakthrough drug now available at affordable prices in India.
NUPARP: Manufactere by ZYDUS Cadila
Nuparp is administered to patients who have undergone full or partial treatment for their cancer with platinum-based drugs. Patients are treated with this medication as a maintenance regimen.
Rucaparib Price in India
Now, let’s take a look at the costs of Rucaparib in India here.
Rucaparib 200 mg price in India for a bottle of 60 tablets –
- NUPARP – INR 39055
- BDPARIB – INR 42400
Rucaparib 300 mg price in India for a bottle of 60 tablets –
- BDPARIB – INR 49680
- NUPARP – INR 43517
Rucaparib 400 mg and Rucaparib 600 mg price in India are the cheap as compared to the others.
Source: 1mg.com
Rucaparib role in prostate cancer treatment
Rubraca is instrumental in the treatment of castration-resistant prostate cancer that doesn’t respond to medical or surgical treatment any longer that aims at lowering testosterone.
It is meant to be administered among the patients that have the aforementioned health conditions as well as in those in whose body the cancer has spread. It has a certain type of inherited (germline) or acquired (somatic) abnormal BRCA gene, and you have been treated with certain medicines for your cancer.